Diagnosis, characterization and outcome of ccTGA
Diagnosis, characterization and outcome of congenitally
corrected transposition of the great arteries in the fetus:
a multicenter series of 30 cases
D. PALADINI*, P. VOLPE†, M. MARASINI‡, M. G. RUSSO§, M. VASSALLO*, M. GENTILE¶,and R. CALABR ` O§
*Fetal Cardiology Unit, Department of Gynecology and Obstetrics, University Federico II of Naples and §Department of Pediatric Cardiology, 2nd University of Naples, Monaldi Hospital, Naples, †Department of Obstetrics and Gynecology, ‘‘Di Venere-Giovanni XXIII’’ Hospital and ¶Department of Medical Genetics, I.R.C.C.S. ‘‘Di Venere-Giovanni XXIII’’ Hospital, Bari and ‡Pediatric Cardiology,
I.R.C.C.S. Giannina Gaslini Hospital, Genoa, Italy
Congenitally corrected transposition of the great arteries
(ccTGA) is characterized by atrioventricular and ventriculoarterial discordance. It represents a rare cardiac
defect, accounting for 1.1% of cases of major congenital
heart disease (CHD), and has an incidence at birth of
0.02 per 1000 live births. Prenatal diagnosis of this
lesion is feasible but may be difficult to detect at routine
screening because the atrioventricular discordance may
be overlooked if other significant anomalies of the fourchamber
view are absent.
